Tuesday, October 14, 2008

VIAGRA (Drug Description)

VIAGRA®
(sildenafil citrate) Tablets

DRUG DESCRIPTION

VIAGRA®, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

Sildenafil citrate is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H- pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate and has the following structural formula:

VIAGRA (sildenafil citrate) structural formula illustration

Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water and a molecular weight of 666.7. VIAGRA (sildenafil citrate) is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg and 100 mg of sildenafil for oral administration. In addition to the active ingredient, sildenafil citrate, each tablet contains the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #2 aluminum lake.

1 comments:

Dr.DianaFassett said...

Viagra, the FDA (Food and Drugs Administration) approved anti-impotence drug is composed of specific inactive ingredients such as anhydrous dibasic calcium phosphate, microcrystalline cellulose, magnesium stearate et al and altogether the medicine contains sildenafil as the chief component. But the erectile dysfunction medicine viagra would yield effective results only when taken in accordance with the instructions of the doctor.